High-Intensity Interval Training Attenuates Insulin Resistance Induced by Sleep Deprivation in Healthy Males

نویسندگان

  • Jorge F. T. de Souza
  • Murilo Dáttilo
  • Marco T. de Mello
  • Sergio Tufik
  • Hanna K. M. Antunes
چکیده

Introduction: Sleep deprivation can impair several physiological systems and recently, new evidence has pointed to the relationship between a lack of sleep and carbohydrate metabolism, consequently resulting in insulin resistance. To minimize this effect, High-Intensity Interval Training (HIIT) is emerging as a potential strategy. Objective: The aim of this study was to investigate the effects of HIIT on insulin resistance induced by sleep deprivation. Method: Eleven healthy male volunteers were recruited, aged 18-35 years, who declared taking 7-8 h sleep per night. All volunteers were submitted to four different conditions: a single night of regular sleep (RS condition), 24 h of total sleep deprivation (SD condition), HIIT training followed by regular sleep (HIIT+RS condition), and HIIT training followed by 24 h of total sleep deprivation (HIIT+SD condition). They performed six training sessions over 2 weeks and each session consisted of 8-12 × 60 s intervals at 100% of peak power output. In each experimental condition, tests for glucose, insulin, cortisol, free fatty acids, and insulin sensitivity, measured by oral glucose tolerance test (OGTT), were performed. Results: Sleep deprivation increased glycaemia and insulin levels, as well as the area under the curve. Furthermore, an increase in free fatty acids concentrations and basal metabolism was observed. There were no differences in the concentrations of cortisol. However, HIIT before 24 h of sleep deprivation attenuated the increase of glucose, insulin, and free fatty acids. Conclusion: Twenty-four hours of sleep deprivation resulted in acute insulin resistance. However, HIIT is an effective strategy to minimize the deleterious effects promoted by this condition.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The effect of eight weeks of high-intensity interval training and sleep regulation on resistance and sensitivity of insulin, body fat percentage, and reaction time in adolescent girls with sleep disorders

Background and Aims: Sleep disorders increase many diseases and a decrease physiological function. This study aimed to compare the effect of the two methods of high-intensity interval training (HIIT) and sleep regulation program and a combination of the two on insulin resistance and sensitivity, body fat percentage, and reaction time in adolescents with sleep disorders. Materials and Methods: ...

متن کامل

The effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats

Introduction. The aim of this study was to investigate the effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats.  Method. Forty male rats were divided into two groups: high-fat diet (HFD; n=32) and standard diet (C; n=8). After 10 weeks inducing obesity, eight rats from the HFD and C groups were sacrifi...

متن کامل

Effect of High Intensity Interval Training on FTO Gene Expression in Subcutaneous Fatty Tissue of Diabetic Wistar Rats

Background: Fat mass and obesity-associated gene (FTO) is directly associated with increased risk of obesity and type 2 diabetes mellitus (T2DM). The purpose of this study was to investigate the effect of 12 weeks of high intensity interval training (HIIT) on FTO expression of subcutaneous fat tissue in T2DM rats. Methods: In this experimental study, twelve males Wistar rats (220±10 g) with T2...

متن کامل

Effect of High Intensity Interval Training and Portulaca Oleracea Supplement on Changes in Fetuin A Level and Insulin Resistance in Rats with Non-Alcoholic Fatty Liver Disease

Background and purpose: The aim of the present study was to investigate the effect of high intensity interval training (HIIT) and Portulaca Oleracea supplementation on fetuin level and insulin resistance of rat with NAFLD. Materials and methods: 25 male Wistar rats randomly divided into 5 groups: healthy control (n = 5), fatty liver control (n = 5), supplement. (N = 5), HIIT (n = 5) and HIIT+...

متن کامل

Effect of Eight Weeks of High Intensity Interval Training on Insulin Resistance and IRS1 Gene Expression in Gastrocnemius Muscle of Obese Wistar Rats

Background and objectives: The role of genetic components in expression of proteins involved in signaling pathways of fat and carbohydrate metabolism has been well-demonstrated. The aim of this study was to determine effects of high intensity interval training (HIIT) on glucose, insulin, and insulin resistance levels as well as IRS1 expression in gastrocnemius muscle of obese Wistar rats. Meth...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2017